IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma
نویسندگان
چکیده
منابع مشابه
IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma
Esophageal adenocarcinoma (EAC) patients commonly present with advanced stage disease and demonstrate resistance to therapy, with response rates below 40%. Understanding the molecular mechanisms of resistance is crucial for improvement of clinical outcomes. IGFBP2 is a member of the IGFBP family of proteins that has been reported to modulate both IGF and integrin signaling and is a mediator of ...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2015
ISSN: 1949-2553
DOI: 10.18632/oncotarget.4532